Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials. 1st ed. 2020, Paperback/Meinhard Kieser

This book provides an extensive overview of the principles and methods of sample size calculation and recalculation in clinical trials. Blinded sample size recalculation procedures for internal pilot study designs are considered, as well as methods for sample size reassessment in adaptive designs that use unblinded data from interim analyses. Publisher: Springer Nature Switzerland AG Author(s): Meinhard Kieser Illustration(s): 126 Illustrations, black and white; XIV, 396 p. 126 illus. Number of pages: 396 Collection: Springer Series in Pharmaceutical Statistics Publication date: 2021 Dimensions: 155 x 234 x 24 Cover type: Paperback / softback